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481039627
Neurons IonicCurrents
View Neurons IonicCurrents Records 68 records
  ID Neurons 481039627  
  ID Methods Electrophysiology -1020917390  
  Current name I(NaP)  
  Charge carrier Na+  
  Peak conductance -  
  Peak current (Fig. 2)  
  E rev -  
  V threshold about -60 mV  
  V half activation -  
  V peak -40 to - 35 mV  
  Citations "As has also been found for the fast INa during development (Huguenard et al.
1988), the voltage dependence of INaP activation did not change during the
time frame of out study. However, INaP seemed to increase in magnitude during
development (Fig. 1A)."

"As shown in the histogram of Fig. 2A, the strongest increase in INaP
amplitude ocurred between aoung and juvenile rats where the mean peak INaP
amplitude more than doubled, whereas a smaller increase was seen from juvenile
to mature rats."

"Surprisingly, only a rather weak correlation (r=0.61)was found between age
amd maximal current density."
 
  Reference figures Fig. 1, 2.  
  Reference text pp.291-292  
  Comments Persistent sodium current was completely blocked by TTX.  
Methods Electrophysiology.ID Ref. -1020917390  
Neurons.ID Ref. 481039627  

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