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35614620
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Neurons IonicCurrents
68 records
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single-channel Na+ currents from cell-attached patches. Examples of
single-channel currents from a P10 neuron are shown in Fig.10B. Single-step
depolarizations resulted in a barrage of early channel openings, as well as
late individual events with latencies of up to tens of milliseconds.
Occasionally bursts of openings were seen that lasted the duration of of the
depolarization. Ensemble averages of Na+ channel currents demonstrated two
decay components, with similar time constants to those obtained with
whole-cell clamp currents (Fig.10B). No significant differences in the
amplitudes of the early and late single-channel openings could be
detected."pp.790-791.
