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-9806123
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Neurons IonicCurrents
68 records
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average) activated by voltage commands in a somatic patch, and Fig. 3B,
location 2 shows comparable recordings from a dendritic patch about 80 µm away
(see locations 1 and 2 in Fig. 3A). Fig. 3B, locations 3 and show recordings
from 2 additional sites [located at the junction of soma and apical dendrite
(location 3 if Fig. 3 A and B) and further distal on the dendrite (location 4
in Fig. 3 A and B)] from the same neuron. Note that although there was Na+
channel activity at each location, the density of channels was not precisely
equivalent at all locations. For example, the dendritic location in Fig. 3A,
location 4 had an unusually high level of Na+ current; this would be
indicative of a " hot spot" (16, 17). All recordings showed transient (about 1
msec) inward openings that were activated in a similar pattern by each voltage
command at a given site (compare sequential sweeps in each vertical column of
Fig.3B)."
