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Neurons IonicCurrents
68 records
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dendrites (Oakley et al. 2001). In the present study, the spatial extent of
these plateaus were examined on two cells. Figure 6 shows the results obtained
in one of these cells. Focal glutamate iontophoresis at a site 128 µm from the
soma on a basal dendrite evoked an all-(red trace, bottom)-or-none (gray
trace, bottom) plateau. The corresponding pseudocolor plot (Fog. 6, top) shows
that the plateau was restricted to a small region surrounding the
iontophoretic site (indicated by dashed line in pseudocolor plot). A 50%
contour drawn around the region estimates the proximal extent of the plateau
as 16 µm and the distal extent as 15 µm. In this cell, the spatial extent of
the plateau was no significantly changed when 100 µm AP-5 was added to the
bath and the experiment was repeated (data not shown). In the second cell
tested, iontophoresis at a site 105 µm from the soma evoked a plateau, which
was estimated to extend 20 µm proximally and 10 µm distally."p.510
